Muscle Mania

Neurological abnormalities and intellectual disability are prevalent in some forms of muscular dystrophy. Approaches to enhance mitochondrial function in DMD have also been studied. These compounds are expected to decrease oxidative tension and fibrosis. In addition, histone deacetylase inhibition has been explored as a system to enhance regeneration and decrease inflammation in sufferers with DMD. Givinostat was tested in a compact open-label study, where therapy decreased fibrosis in all patients…Read More